Nested EASE (nEASE) is an extension of EASE. The nEASE algorithm includes a second, sub-level, iterative Fisher’s Exact Test on significantly enriched GO terms identified in a first-level EASE analysis. This sub-classification approach provides increased sensitivity for detecting enriched GO terms and thus affords a deeper understanding of possible mechanisms underlying a given condition under study. nEASE was added to MeV as a new feature for version 4.5.

Begin this tutorial after installing MeV.